How does THC make you feel high?

The "high" of THC comes from a chemical called dopamine. Dopamine is released by the brain to reward us for behavior that, historically, has improved our chance of survival. This neurotransmitter is crucial for the brain's reward system, associated with feelings of pleasure and satisfaction.

THC can increase dopamine release by affecting the areas of the brain that regulate dopamine production. It does this by inhibiting the neurons that typically inhibit dopamine release, essentially removing the "brakes" on dopamine production. This increase in dopamine contributes to the euphoria, heightened sensory perception, and altered sense of time commonly experienced with cannabis use.

THC also takes over the regulation that is usually handled by Anandamide. Anandamide, playfully nicknamed "the bliss molecule," is a naturally occurring cannabinoid in our bodies that plays a pivotal role in regulating our mood, happiness, and overall sense of well-being. Think of it as your body's own built-in happiness booster. Its name is derived from "Ananda," the Sanskrit word for "joy, bliss, delight," and it truly lives up to its name by influencing aspects of our brain responsible for pleasure, appetite, and memory.

Anandamide works by binding to cannabinoid receptors in the brain and throughout the body, part of the endocannabinoid system that helps maintain balance and homeostasis. It's like a natural pacifier, easing stress and promoting peace of mind.

THC closely mimics the structure of anandamide, which allows it to bind with cannabinoid receptors in our endocannabinoid system, especially in the brain. When THC latches on, it can amplify the feelings of euphoria and peace that anandamide naturally provides. Maintaining a healthy balance is key to sustaining our natural state of bliss and well-being.